Clinical pharmacology and metabolism of mitoxantrone
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چکیده
منابع مشابه
Excretion and Metabolism of Mitoxantrone in Rabbits1
The hepatic clearance of mitoxantrone was evaluated in rabbits using both bile-duct cannulated animals and freshly isolated hepatocytes in suspension or in primary culture. Mitoxantrone metabolic behavior was assessed by high-performance liquid chromatography using a method which specifically resolved mitoxantrone from its monoand dicarboxylic acid derivatives. Excretion of mitoxantrone in bile...
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ژورنال
عنوان ژورنال: Journal of Cancer Research and Clinical Oncology
سال: 1986
ISSN: 0171-5216,1432-1335
DOI: 10.1007/bf02579819